Roma vs Lecce Prediction, Odds & Betting Tips — Serie A 22 Mar 2026

For Lecce, the stakes are high as they battle to avoid the drop. Their recent form has seen them score 6 and concede 8 goals in their last 5 matches, indicating a need for improvement in both defense and attack. Roma, with their superior goal difference and league position, are favorites to take all three points.

The news of Koné's injury is a significant blow to Roma, as he has been a key player. However, with 50% of their players in form, Roma still have the talent to outperform Lecce, who have 60% of their players in form. Roma's ability to create scoring opportunities, especially at home, will be crucial in deciding the outcome of the match.

The head-to-head record also shows that Roma have averaged 1.5 goals per game against Lecce, while Lecce have failed to score in these matches. This significant goal difference in their historical encounters indicates that Roma are likely to control the tempo of the game and create more scoring opportunities.

Roma's ability to score goals, especially at home, is a key factor in their favor. With an average of 2.67 goals scored per match at the Stadio Olimpico, Roma will be confident of breaking down Lecce's defense. The return of key players to fitness and the home advantage will also play a significant role in determining the outcome.